Brazilian Green Propolis is consider the best of the world. It contains high levels of flavonoids and phenolic compounds that increase your body resistance against diseases. Phytoflora Propolis is a propolis very high concentrated. It contains around 5 times more propolis than the common capsules. Its concentration is equivalent of 40 drops of a high concentrated propolis extract.
TAKE CARE WITH SOME BRANDS THAT SHOWS 500 MG OR OVER.
Important is to know how much Propolis Resin (active ingredient) it contains.
OUR PHYTOFLORA PROPOLIS 400MG CAPSULES HAS THE HIGHEST CONTENTS OF PROPOLIS IN THE MARKET.
Published in Cancer Detection and Prevention
1998; 22(6):506-515.
Apoptosis and Suppression of Tumor
Growth by Artepillin C Extracted From Brazilian Propolis
Tetsuo Kimoto, M.D., Ph.D.,a Shigeyuki
Arai, D.V.M., Ph.D.,a Michihiro Kohguchi, B.S., a Miho Aga, B.Pharm.,a Yutaka
Nomura, B.S., a Mark J. Micallef, Ph.D.,a Masashi Kurimoto, M.S.,a and Keiichiro
Mito, Ph.D.b
ABSTRACT: Artepillin C
was extracted from Brazilian propolis. Artepillin C
(3,5-diprenyl-4-hydroxycinnamic acid) has a molecular weight of 300.40 and
possesses antibacterial activity. When artepillin C was applied to human and
murine malignant tumor cells in vitro and in vivo, artepillin C
exhibited a cytotoxic effect and the growth of tumor cells was clearly
inhibited. The artepillin C was found to cause significant damage to solid tumor
and leukemic cells by the MTT assay, DNA synthesis assay, and morphological
observation in vitro. When xenografts of human tumor cells were
transplanted into nude mice, the cytotoxic effects of artepillin C were most
noticeable in carcinoma and malignant melanoma. Apoptosis, abortive mitosis, and
massive necrosis combined were identified by histological observation after
intratumor injection of 500 μg of artepillin C three times a week. In addition
to suppression of tumor growth, there was an increase in the ratio of CD4/CD8 T
cells, and in the total number of helper T cells. These findings indicate that
artepillin C activates the immune system, and possesses direct antitumor
activity.